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Kent KirshenbaumAssociate Professor of ChemistryB.A., Reed College; Ph.D., University of California, San Francisco; Postdoctoral Fellow, California Institute of Technology Email: kent@nyu.edu Phone: 212-998-8486 Lab Homepage: http://www.nyu.edu/projects/kirshenbaum/ |
Areas of Research/Interest: Bioorganic Chemistry, Biomimetic Chemistry, Protein Conformation and Dynamics, Macromolecular Design
Select Publications:
Shin, S.-B.Y.; Yoo, B.; Todaro, L.; Kirshenbaum, K. "Cyclic Peptoids" J. Am. Chem. Soc., 129: 3218-3225.
Fafarman, A.T., Borbat, P.P., Jack H. Freed, J.H., Kirshenbaum, K. "Characterizing the structure and dynamics of folded oligomers: Pulsed ESR studies of peptoid helices" Chem. Commun., 2007, 377-379.
Utku, Y., Dehan, E., Ouerfelli, O., Piano, F., Zuckermann, R.N., Pagano, M., Kirshenbaum, K. "A peptidomimetic siRNA transfection reagent for highly effective gene silencing" Mol. Biosys. 2006, 2: 312-317.
Anderson, E.A., Isaacman, S., Peabody, D.S., Wang, E.Y., Canary, J.W., Kirshenbaum, K. "Viral nanoparticles donning a paramagnetic coat: Conjugation of MRI contrast agents to the MS2 capsid" Nano Letters, 2006, 6: 1160-1164
Holub, J.M., Jang, H., Kirshenbaum, K. “Clickity-Click: Highly Functionalized Peptoid Oligomers Generated by Sequential Azide-Alkyne [3+2] Cycloadditions on Solid Phase Support” Org. Biomol. Chem. 2006, 4: 1497-1502.
Spencer, T., Yoo, B., Kirshenbaum, K. “Purification and Modification of Fullerene C60 in the Undergraduate Laboratory” J. Chem. Ed. 2006, 83: 1218-1220.
Huang, K., Wu, C.W., Sanborn, T.J., Patch, J.A., Kirshenbaum, K., Zuckermann, R.N., Barron, A.E., Radhakrishnan, I. “A Threaded Loop Conformation Adopted by a Family of Peptoid Nonamers” J. Am. Chem. Soc. 2006, 128: 1733-1738.
Yoo, B., Kirshenbaum, K. “Protease-Mediated Ligation of Abiotic Oligomers” J. Am. Chem. Soc. 2005, 127: 17132-17133.
Holub, J. M., Garabedian, M.J., Kirshenbaum, K. (2007). Peptoids on Steroids: Precise Multivalent Estradiol-Peptidomimetic Conjugates Generated via Azide-Alkyne [3+2] Cycloaddition Reactions. QSAR & Comb. Sci., in press
Holub, J.M., Jang, H., Kirshenbaum, K. (2007). Fit To Be Tied: Conformation-Directed Macrocyclization of Peptoid Foldamers. Org. Lett. 9: 3275-3278.
Fellowships/Honors: National Institutes of Health NRSA Postdoctoral Fellowship, 2000-2002; Frank Goyan Award in Physical Chemistry at UCSF, 1998; University of California Regents Graduate Fellowship, 1994-1995; Alzheimer's Association New Investigator Award, 2005-2007; James D.Watson Investigator Award, 2004-2006; NSF CAREER Award, 2007